The Dose Dependent Effects of Ruxolitinib on the Invasion and Tumorigenesis in Gliomas Cells via Inhibition of Interferon Gamma-Depended JAK/STAT Signaling Pathway

OBJECTIVE: Glioblastoma multiforme (GBM) is the most aggressive for of brain tumor and treatment often fails due to the invasion of tumor cells into neighboring healthy brain tissues. Activation of the Janus kinase-signal transducer and activator of transcription (JAK/STAT) signaling pathway is esse...

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Detalles Bibliográficos
Autores principales: Delen, Emre, Doğanlar, Oğuzhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Neurosurgical Society 2020
Materias:
Laboratory Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365278/
https://www.ncbi.nlm.nih.gov/pubmed/32492985
http://dx.doi.org/10.3340/jkns.2019.0252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365278/
https://www.ncbi.nlm.nih.gov/pubmed/32492985
http://dx.doi.org/10.3340/jkns.2019.0252

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