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Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness

Rationale: Complement is crucial for host defense but may also drive dysregulated inflammation. There is limited understanding of alternative complement function, which can amplify all complement activity, during critical illness. Objectives: We examined the function and key components of the altern...

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Detalles Bibliográficos
Autores principales: Bain, William, Li, Huihua, van der Geest, Rick, Moore, Sara R., Olonisakin, Tolani F., Ahn, Brian, Papke, Erin, Moghbeli, Kaveh, DeSensi, Rebecca, Rapport, Sarah, Saul, Melissa, Hulver, Mei, Xiong, Zeyu, Mallampalli, Rama K., Ray, Prabir, Morris, Alison, Ma, Lina, Doi, Yohei, Zhang, Yingze, Kitsios, Georgios D., Kulkarni, Hrishikesh S., McVerry, Bryan J., Ferreira, Viviana P., Nouraie, Mehdi, Lee, Janet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365364/
https://www.ncbi.nlm.nih.gov/pubmed/32374177
http://dx.doi.org/10.1164/rccm.201910-2083OC