Cargando…
Increased Alternative Complement Pathway Function and Improved Survival during Critical Illness
Rationale: Complement is crucial for host defense but may also drive dysregulated inflammation. There is limited understanding of alternative complement function, which can amplify all complement activity, during critical illness. Objectives: We examined the function and key components of the altern...
Autores principales: | Bain, William, Li, Huihua, van der Geest, Rick, Moore, Sara R., Olonisakin, Tolani F., Ahn, Brian, Papke, Erin, Moghbeli, Kaveh, DeSensi, Rebecca, Rapport, Sarah, Saul, Melissa, Hulver, Mei, Xiong, Zeyu, Mallampalli, Rama K., Ray, Prabir, Morris, Alison, Ma, Lina, Doi, Yohei, Zhang, Yingze, Kitsios, Georgios D., Kulkarni, Hrishikesh S., McVerry, Bryan J., Ferreira, Viviana P., Nouraie, Mehdi, Lee, Janet S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365364/ https://www.ncbi.nlm.nih.gov/pubmed/32374177 http://dx.doi.org/10.1164/rccm.201910-2083OC |
Ejemplares similares
-
Platelets inhibit apoptotic lung epithelial cell death and protect mice against infection-induced lung injury
por: Bain, William, et al.
Publicado: (2019) -
Distinct profiles of host responses between plasma and lower respiratory tract during acute respiratory failure
por: Kitsios, Georgios D., et al.
Publicado: (2023) -
Factor H preserves alternative complement function during ARDS, linked to improved survival
por: Bain, William, et al.
Publicado: (2023) -
Serum metabolomic signatures of fatty acid oxidation defects differentiate host-response subphenotypes of acute respiratory distress syndrome
por: Suber, Tomeka L., et al.
Publicado: (2023) -
Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia
por: Lai, Yandong, et al.
Publicado: (2021)