c-Src functionality controls self-renewal and glucose metabolism in MCF7 breast cancer stem cells

Deregulation of Src kinases is associated with cancer. We previously showed that SrcDN conditional expression in MCF7 cells reduces tumorigenesis and causes tumor regression in mice. However, it remained unclear whether SrcDN affected breast cancer stem cell functionality or it reduced tumor mass. H...

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Detalles Bibliográficos
Autores principales: Mayoral-Varo, Víctor, Calcabrini, Annarica, Sánchez-Bailón, María Pilar, Martínez-Costa, Óscar H., González-Páramos, Cristina, Ciordia, Sergio, Hardisson, David, Aragón, Juan J., Fernández-Moreno, Miguel Ángel, Martín-Pérez, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365443/
https://www.ncbi.nlm.nih.gov/pubmed/32673341
http://dx.doi.org/10.1371/journal.pone.0235850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365443/
https://www.ncbi.nlm.nih.gov/pubmed/32673341
http://dx.doi.org/10.1371/journal.pone.0235850

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