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Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites

Mechanisms of transcriptional control in malaria parasites are still not fully understood. The positioning patterns of G-quadruplex (G4) DNA motifs in the parasite’s AT-rich genome, especially within the var gene family which encodes virulence factors, and in the vicinity of recombination hotspots,...

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Detalles Bibliográficos
Autores principales: Gazanion, Elodie, Lacroix, Laurent, Alberti, Patrizia, Gurung, Pratima, Wein, Sharon, Cheng, Mingpan, Mergny, Jean-Louis, Gomes, Ana Rita, Lopez-Rubio, Jose-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365481/
https://www.ncbi.nlm.nih.gov/pubmed/32628663
http://dx.doi.org/10.1371/journal.pgen.1008917