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Genome wide distribution of G-quadruplexes and their impact on gene expression in malaria parasites
Mechanisms of transcriptional control in malaria parasites are still not fully understood. The positioning patterns of G-quadruplex (G4) DNA motifs in the parasite’s AT-rich genome, especially within the var gene family which encodes virulence factors, and in the vicinity of recombination hotspots,...
Autores principales: | Gazanion, Elodie, Lacroix, Laurent, Alberti, Patrizia, Gurung, Pratima, Wein, Sharon, Cheng, Mingpan, Mergny, Jean-Louis, Gomes, Ana Rita, Lopez-Rubio, Jose-Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365481/ https://www.ncbi.nlm.nih.gov/pubmed/32628663 http://dx.doi.org/10.1371/journal.pgen.1008917 |
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