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Active Metabolite of Aeruginascin (4-Hydroxy-N,N,N-trimethyltryptamine): Synthesis, Structure, and Serotonergic Binding Affinity

[Image: see text] The putative active metabolite of aeruginascin, a naturally occurring tryptamine of “magic mushrooms,” has been synthesized and structurally characterized. Competitive radioligand binding assays demonstrate that it has a high affinity at human serotonin receptors 5-HT(1A), 5-HT(2A)...

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Detalles Bibliográficos
Autores principales: Chadeayne, Andrew R., Pham, Duyen N. K., Reid, Brian G., Golen, James A., Manke, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365549/
https://www.ncbi.nlm.nih.gov/pubmed/32685863
http://dx.doi.org/10.1021/acsomega.0c02208