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E-cadherin is required for metastasis in multiple models of breast cancer

Metastasis is the major driver of cancer deaths and begins when cancer cells invade surrounding tissues. Invasion and metastasis have been proposed to initiate following loss of the intercellular adhesion protein, E-cadherin (E-cad)(1,2), based upon inverse correlations between in vitro migration an...

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Detalles Bibliográficos
Autores principales: Padmanaban, Veena, Krol, Ilona, Suhail, Yasir, Szczerba, Barbara M., Aceto, Nicola, Bader, Joel S., Ewald, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365572/
https://www.ncbi.nlm.nih.gov/pubmed/31485072
http://dx.doi.org/10.1038/s41586-019-1526-3