Cargando…

E-cadherin is required for metastasis in multiple models of breast cancer

Metastasis is the major driver of cancer deaths and begins when cancer cells invade surrounding tissues. Invasion and metastasis have been proposed to initiate following loss of the intercellular adhesion protein, E-cadherin (E-cad)(1,2), based upon inverse correlations between in vitro migration an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Padmanaban, Veena, Krol, Ilona, Suhail, Yasir, Szczerba, Barbara M., Aceto, Nicola, Bader, Joel S., Ewald, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365572/ https://www.ncbi.nlm.nih.gov/pubmed/31485072 http://dx.doi.org/10.1038/s41586-019-1526-3

Ejemplares similares

Recent advances in the biology of human circulating tumour cells and metastasis
por: Gkountela, Sofia, et al.
Publicado: (2016)

Twist1-induced dissemination preserves epithelial identity and requires E-cadherin
por: Shamir, Eliah R., et al.
Publicado: (2014)

Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer
por: Balamurugan, Kuppusamy, et al.
Publicado: (2023)

Between-tumor and within-tumor heterogeneity in invasive potential
por: Padmanaban, Veena, et al.
Publicado: (2020)

Cancer cells educate natural killer cells to a metastasis-promoting cell state
por: Chan, Isaac S., et al.
Publicado: (2020)

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding
por: Gkountela, Sofia, et al.
Publicado: (2019)

Loss of E-cadherin and epithelial to mesenchymal transition is not required for cell motility in tissues or for metastasis
por: Liu, Xiang, et al.
Publicado: (2014)

Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer
por: Vetter, Marcus, et al.
Publicado: (2018)

Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin
por: Wijshake, Tobias, et al.
Publicado: (2021)

E-cadherin relates to EGFR expression and lymph node metastasis in primary breast carcinoma.
por: Jones, J. L., et al.
Publicado: (1996)

MicroRNA-10b targets E-cadherin and modulates breast cancer metastasis
por: Liu, Yong, et al.
Publicado: (2012)

E-cadherin interactions are required for Langerhans cell differentiation
por: Mayumi, Nobuko, et al.
Publicado: (2013)

E‐cadherin deregulation in breast cancer
por: Corso, Giovanni, et al.
Publicado: (2020)

E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements
por: Christgen, Matthias, et al.
Publicado: (2020)

Ajuba is required for Rac activation and maintenance of E-cadherin adhesion
por: Nola, Sébastien, et al.
Publicado: (2011)

Friend or foe: role of E-cadherin in prostate cancer metastasis
por: Lin, Ching-Yu, et al.
Publicado: (2016)

Down-regulation of epithelial cadherin is required to initiate metastatic outgrowth of breast cancer
por: Wendt, Michael K., et al.
Publicado: (2011)

Quantification of Protein Secretion from Circulating Tumor Cells in Microfluidic Chambers
por: Armbrecht, Lucas, et al.
Publicado: (2020)

Adhesive But Not Lateral E-cadherin Complexes Require Calcium and Catenins for Their Formation
por: Chitaev, Nikolai A., et al.
Publicado: (1998)

MTA1 promotes metastasis of MPM via suppression of E-cadherin
por: Xu, Caihua, et al.
Publicado: (2015)

Alterations of MEN1 and E-cadherin/β-catenin complex in sporadic pulmonary carcinoids
por: VESCHI, SERENA, et al.
Publicado: (2012)

N-Cadherin Promotes Motility in Human Breast Cancer Cells Regardless of Their E-Cadherin Expression
por: Nieman, Marvin T., et al.
Publicado: (1999)

The expressions of NEDD9 and E-cadherin correlate with metastasis and poor prognosis in triple-negative breast cancer patients
por: Li, Peng, et al.
Publicado: (2016)

E-Cadherin as a diagnostic biomarker in breast cancer
por: Singhai, Rajeev, et al.
Publicado: (2011)

E-cadherin is Required for the Homeostasis of Lgr5(+) Gastric Antral Stem Cells
por: Tang, Yuling, et al.
Publicado: (2019)

E-cadherin expression in renal cell cancer and its significance in metastasis and survival.
por: Katagiri, A., et al.
Publicado: (1995)

Cellular senescence promotes cancer metastasis by enhancing soluble E-cadherin production
por: Kawaguchi, Koichiro, et al.
Publicado: (2021)

TMEM139 prevents NSCLC metastasis by inhibiting lysosomal degradation of E‐cadherin
por: Zhang, Shuai, et al.
Publicado: (2022)

Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin
por: Hugo, H. J., et al.
Publicado: (2017)

Association of quantitative analysis of intratumoral reduced E-cadherin expression with lymph node metastasis and prognosis in patients with breast cancer
por: Meng, Xiangyue, et al.
Publicado: (2023)

P-cadherin and the journey to cancer metastasis
por: Vieira, André Filipe, et al.
Publicado: (2015)

Stem-like features of cancer cells on their way to metastasis
por: Gkountela, Sofia, et al.
Publicado: (2016)

VEGF Mediates Tumor Growth and Metastasis by Affecting the Expression of E-Cadherin and N-Cadherin Promoting Epithelial to Mesenchymal Transition in Gastric Cancer
por: Zhang, Yue, et al.
Publicado: (2023)

E-cadherin as a prognostic indicator in primary breast cancer
por: Parker, C, et al.
Publicado: (2001)

In breast carcinoma dysadherin expression is correlated with invasiveness but not with E-cadherin
por: Batistatou, A, et al.
Publicado: (2007)

Significance of E-cadherin expression in triple-negative breast cancer
por: Kashiwagi, S, et al.
Publicado: (2010)

Low frequency of E-cadherin alterations in familial breast cancer
por: Salahshor, Sima, et al.
Publicado: (2001)

Levels of Soluble E-Cadherin in Breast, Gastric, and Colorectal Cancers
por: Repetto, Ombretta, et al.
Publicado: (2014)

The Autophagy Machinery Contributes to E-cadherin Turnover in Breast Cancer
por: Damiano, Valentina, et al.
Publicado: (2020)

The role of E-Cadherin expression in primary site of breast cancer
por: Karsten, Nora, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_csa1tmhvsshsqhl8lp3gue2nbh