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VASH-1 Regulates Oxidative Stress and Fibrosis in Diabetic Kidney Disease via SIRT1/HIF1α and TGFβ1/Smad3 Signaling Pathways

Aims: To investigate the role of Vasohibin-1 (VASH-1), silence information adjustment factor 2-related enzyme 1 (SIRT1)/hypoxic-inducible factor 1α (HIF1α) and transforming growth factor-β1 (TGFβ1) /Smad3 signaling pathways in oxidative stress and fibrosis of diabetic kidney disease (DKD). Materials...

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Detalles Bibliográficos
Autores principales: Ren, Huiwen, Shao, Ying, Wu, Can, Lv, Chuan, Zhou, Yang, Wang, Qiuyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365843/
https://www.ncbi.nlm.nih.gov/pubmed/32754616
http://dx.doi.org/10.3389/fmolb.2020.00137