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Therapeutic Effects of Simultaneous Delivery of Nerve Growth Factor mRNA and Protein via Exosomes on Cerebral Ischemia

Stroke is the leading neurological cause of death and disability all over the world, with few effective drugs. Nerve growth factor (NGF) is well known for its multifaceted neuroprotective functions post-ischemia. However, the lack of an efficient approach to systemically deliver bioactive NGF into i...

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Detalles Bibliográficos
Autores principales: Yang, Jialei, Wu, Shipo, Hou, Lihua, Zhu, Danni, Yin, Shimin, Yang, Guodong, Wang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7365960/
https://www.ncbi.nlm.nih.gov/pubmed/32682291
http://dx.doi.org/10.1016/j.omtn.2020.06.013