In vitro activity of omadacycline and levofloxacin against Escherichia coli, Klebsiella pneumoniae and Staphylococcus saprophyticus in human urine supplemented with calcium and magnesium

BACKGROUND: Omadacycline, an aminomethylcycline, was approved in 2018 for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. In a Phase Ib study, around 34% of the absorbed dose of omadacycline was shown to be excreted in urine—an importan...

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Detalles Bibliográficos
Autores principales: Pagano, Paul, Marra, Andrea, Shinabarger, Dean, Pillar, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366199/
https://www.ncbi.nlm.nih.gov/pubmed/32428235
http://dx.doi.org/10.1093/jac/dkaa138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366199/
https://www.ncbi.nlm.nih.gov/pubmed/32428235
http://dx.doi.org/10.1093/jac/dkaa138

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