Development and Application of a LC-MS/MS Method for Simultaneous Quantification of Four First-Line Antituberculosis Drugs in Human Serum

A simple, rapid, and sensitive liquid chromatography (LC)/mass spectrometry (MS) method was established and validated for simultaneous quantitation of pyrazinamide, isoniazid, rifampicin, and ethambutol in human blood sample. Samples were pretreated by a single-step precipitation with acetonitrile....

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Detalles Bibliográficos
Autores principales: Zheng, Yunliang, Xu, Nana, Hu, Xingjiang, Zhang, Qiao, Liu, Yanpeng, Zhao, Qingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366203/
https://www.ncbi.nlm.nih.gov/pubmed/32724703
http://dx.doi.org/10.1155/2020/8838219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366203/
https://www.ncbi.nlm.nih.gov/pubmed/32724703
http://dx.doi.org/10.1155/2020/8838219

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