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The effect of lumbar puncture on the neurodegeneration biomarker neurofilament light in macaque monkeys

INTRODUCTION: Neurofilament light (NFL) in cerebrospinal fluid (CSF) is elevated in neurodegenerative disease patients, and may track disease progression and treatment. Macaque monkeys are emerging as important translational models of neurodegeneration, and NFL may be a useful biomarker. METHODS: To...

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Detalles Bibliográficos
Autores principales: Boehnke, Susan E., Robertson, Emma L., Armitage‐Brown, Brittney, Wither, Robert G., Lyra e Silva, Natalia M., Winterborn, Andrew, Levy, Ron, Cook, Douglas J., De Felice, Fernanda G., Munoz, Douglas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366296/
https://www.ncbi.nlm.nih.gov/pubmed/32695873
http://dx.doi.org/10.1002/dad2.12069