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Highly Catalytic Enantioselective Reformatsky Reaction with Aldehydes and Ketones Using an Available Prolinol Ligand

[Image: see text] A highly Me(2)Zn-mediated catalytic enantioselective Reformatsky reaction of aldehydes and ketones with ethyl iodoacetate using a readily available prolinol ligand is reported. This reaction provides an efficient method for the construction of β-hydroxy esters in up to 98% yield an...

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Detalles Bibliográficos
Autores principales: Ouyang, Lu, Xia, YanPing, Wei, YiFei, Liao, Jianhua, Luo, Renshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366354/
https://www.ncbi.nlm.nih.gov/pubmed/32685867
http://dx.doi.org/10.1021/acsomega.0c02400