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Association of distinct type 1 bone morphogenetic protein receptors with different molecular pathways and survival outcomes in neuroblastoma

Neuroblastoma (NB) is a paediatric cancer that arises in the sympathetic nervous system. Patients with stage 4 tumours have poor outcomes and 20% of high-risk cases have MYCN amplification. The bone morphogenetic proteins (BMPs) play roles in sympathetic neuritogenesis, by signalling through bone mo...

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Detalles Bibliográficos
Autores principales: Alshangiti, Amnah M., Wyatt, Sean L., McCarthy, Erin, Collins, Louise M., Hegarty, Shane V., Sullivan, Aideen M., O’Keeffe, Gerard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366490/
https://www.ncbi.nlm.nih.gov/pubmed/32714600
http://dx.doi.org/10.1042/NS20200006