Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes

Rapidly increasing availability of genomic data and ensuing identification of disease associated mutations allows for an unbiased insight into genetic drivers of disease development. However, determination of molecular mechanisms by which individual genomic changes affect biochemical processes remai...

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Detalles Bibliográficos
Autores principales: Mehnert, Martin, Ciuffa, Rodolfo, Frommelt, Fabian, Uliana, Federico, van Drogen, Audrey, Ruminski, Kilian, Gstaiger, Matthias, Aebersold, Ruedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366679/
https://www.ncbi.nlm.nih.gov/pubmed/32678104
http://dx.doi.org/10.1038/s41467-020-17387-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366679/
https://www.ncbi.nlm.nih.gov/pubmed/32678104
http://dx.doi.org/10.1038/s41467-020-17387-y

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