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Multi-layered proteomic analyses decode compositional and functional effects of cancer mutations on kinase complexes
Rapidly increasing availability of genomic data and ensuing identification of disease associated mutations allows for an unbiased insight into genetic drivers of disease development. However, determination of molecular mechanisms by which individual genomic changes affect biochemical processes remai...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366679/ https://www.ncbi.nlm.nih.gov/pubmed/32678104 http://dx.doi.org/10.1038/s41467-020-17387-y |