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Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans

Neurodegenerative disorders (ND) like Alzheimer’s (AD), Parkinson’s (PD), Huntington’s or Prion diseases share similar pathological features. They are all age dependent and are often associated with disruptions in analogous metabolic processes such as protein aggregation and oxidative stress, both o...

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Detalles Bibliográficos
Autores principales: Pretsch, Dagmar, Rollinger, Judith Maria, Schmid, Axel, Genov, Miroslav, Wöhrer, Teresa, Krenn, Liselotte, Moloney, Mark, Kasture, Ameya, Hummel, Thomas, Pretsch, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366685/
https://www.ncbi.nlm.nih.gov/pubmed/32678125
http://dx.doi.org/10.1038/s41598-020-68561-7