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Baicalin Suppresses Bilirubin-Induced Apoptosis and Inflammation by Regulating p38 Mitogen-Activated Protein Kinases (MAPK) Signaling in Neonatal Neurons

BACKGROUND: Hyperbilirubinemia is associated with central nervous system damage in preterm neonates due to the neurotoxicity of bilirubin. This study explored the possible mechanisms of bilirubin’s neurotoxicity, and the protective effect of baicalin (BAI) was also investigated. MATERIAL/METHODS: Is...

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Detalles Bibliográficos
Autores principales: Shi, Shuang, Cui, Qianwei, Xu, Jing, Tang, Zhiguo, Shi, Binya, Liu, Zhongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366788/
https://www.ncbi.nlm.nih.gov/pubmed/32633271
http://dx.doi.org/10.12659/MSM.926441