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Whole-Cell Photobleaching Reveals Time-Dependent Compartmentalization of Soluble Proteins by the Axon Initial Segment

By limiting protein exchange between the soma and the axon, the axon initial segment (AIS) enables the segregation of specific proteins and hence the differentiation of the somatodendritic compartment and the axonal compartment. Electron microscopy and super-resolution fluorescence imaging have prov...

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Detalles Bibliográficos
Autores principales: Nicholson, LaShae, Gervasi, Nicolas, Falières, Thibault, Leroy, Adrien, Miremont, Dorian, Zala, Diana, Hanus, Cyril
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366827/
https://www.ncbi.nlm.nih.gov/pubmed/32754013
http://dx.doi.org/10.3389/fncel.2020.00180