Berberine Ameliorates Subarachnoid Hemorrhage Injury via Induction of Sirtuin 1 and Inhibiting HMGB1/Nf-κB Pathway

Excessive cerebral inflammation plays a key role in early brain injury (EBI) after subarachnoid hemorrhage (SAH). Berberine, an isoquinoline alkaloid isolated from Chinese herb Coptis chinensis, possesses anti-inflammatory, and neuroprotective effects. Here we evaluated the beneficial effects of ber...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang-Hua, Peng, Lei, Zhang, Jing, Dong, Yi-Peng, Wang, Cheng-Jun, Liu, Cang, Xia, Da-Yong, Zhang, Xiang-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366844/
https://www.ncbi.nlm.nih.gov/pubmed/32754040
http://dx.doi.org/10.3389/fphar.2020.01073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366844/
https://www.ncbi.nlm.nih.gov/pubmed/32754040
http://dx.doi.org/10.3389/fphar.2020.01073

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