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Dysregulation of HULC promotes contrast-induced nephropathy (CIN) via regulating signaling pathway of miRNA-512 and prostaglandin E1 (PGE(1))

It has been shown that contrast-induced nephropathy (CIN) can be attenuated by the administration of PGE1. As an enzyme responsible for the production of PGE1, PTGS1 was confirmed in this study as a miR-512 target. Meanwhile, HULC has been identified as a competing endogenous RNA of miR-512. Therefo...

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Detalles Bibliográficos
Autores principales: Zhang, Liang, Li, Pan, Zhang, Bi-li, Yu, Man-li, Xu, Rong-liang, Wu, Hong, Chen, Shao-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366906/
https://www.ncbi.nlm.nih.gov/pubmed/32678165
http://dx.doi.org/10.1038/s41598-020-68634-7