Response of spike-wave discharges in aged APP/PS1 Alzheimer model mice to antiepileptic, metabolic and cholinergic drugs

Epileptic nonconvulsive spike-wave discharges (SWDs) are commonly seen in amyloid plaque bearing transgenic mice but only rarely in their wild-type littermates. To shed light on their possible treatment options, we assessed the effect of drugs with variable and known mechanisms of action on the occu...

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Detalles Bibliográficos
Autores principales: Jin, Nanxiang, Ziyatdinova, Sofya, Gureviciene, Irina, Tanila, Heikki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366932/
https://www.ncbi.nlm.nih.gov/pubmed/32678276
http://dx.doi.org/10.1038/s41598-020-68845-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366932/
https://www.ncbi.nlm.nih.gov/pubmed/32678276
http://dx.doi.org/10.1038/s41598-020-68845-y

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