The integrity of cochlear hair cells is established and maintained through the localization of Dia1 at apical junctional complexes and stereocilia

Dia1, which belongs to the diaphanous-related formin family, influences a variety of cellular processes through straight actin elongation activity. Recently, novel DIA1 mutants such as p.R1213X (p.R1204X) and p.A265S, have been reported to cause an autosomal dominant sensorineural hearing loss (DFNA...

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Detalles Bibliográficos
Autores principales: Ninoyu, Yuzuru, Sakaguchi, Hirofumi, Lin, Chen, Suzuki, Toshiaki, Hirano, Shigeru, Hisa, Yasuo, Saito, Naoaki, Ueyama, Takehiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366933/
https://www.ncbi.nlm.nih.gov/pubmed/32678080
http://dx.doi.org/10.1038/s41419-020-02743-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366933/
https://www.ncbi.nlm.nih.gov/pubmed/32678080
http://dx.doi.org/10.1038/s41419-020-02743-z

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