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The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity

The spike protein of SARS-CoV-2 has been undergoing mutations and is highly glycosylated. It is critically important to investigate the biological significance of these mutations. Here, we investigated 80 variants and 26 glycosylation site modifications for the infectivity and reactivity to a panel...

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Detalles Bibliográficos
Autores principales: Li, Qianqian, Wu, Jiajing, Nie, Jianhui, Zhang, Li, Hao, Huan, Liu, Shuo, Zhao, Chenyan, Zhang, Qi, Liu, Huan, Nie, Lingling, Qin, Haiyang, Wang, Meng, Lu, Qiong, Li, Xiaoyu, Sun, Qiyu, Liu, Junkai, Zhang, Linqi, Li, Xuguang, Huang, Weijin, Wang, Youchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366990/
https://www.ncbi.nlm.nih.gov/pubmed/32730807
http://dx.doi.org/10.1016/j.cell.2020.07.012