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The Impact of Mutations in SARS-CoV-2 Spike on Viral Infectivity and Antigenicity
The spike protein of SARS-CoV-2 has been undergoing mutations and is highly glycosylated. It is critically important to investigate the biological significance of these mutations. Here, we investigated 80 variants and 26 glycosylation site modifications for the infectivity and reactivity to a panel...
Autores principales: | Li, Qianqian, Wu, Jiajing, Nie, Jianhui, Zhang, Li, Hao, Huan, Liu, Shuo, Zhao, Chenyan, Zhang, Qi, Liu, Huan, Nie, Lingling, Qin, Haiyang, Wang, Meng, Lu, Qiong, Li, Xiaoyu, Sun, Qiyu, Liu, Junkai, Zhang, Linqi, Li, Xuguang, Huang, Weijin, Wang, Youchun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7366990/ https://www.ncbi.nlm.nih.gov/pubmed/32730807 http://dx.doi.org/10.1016/j.cell.2020.07.012 |
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