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Elevated Glucose Levels Favor SARS-CoV-2 Infection and Monocyte Response through a HIF-1α/Glycolysis-Dependent Axis

COVID-19 can result in severe lung injury. It remained to be determined why diabetic individuals with uncontrolled glucose levels are more prone to develop the severe form of COVID-19. The molecular mechanism underlying SARS-CoV-2 infection and what determines the onset of the cytokine storm found i...

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Detalles Bibliográficos
Autores principales: Codo, Ana Campos, Davanzo, Gustavo Gastão, Monteiro, Lauar de Brito, de Souza, Gabriela Fabiano, Muraro, Stéfanie Primon, Virgilio-da-Silva, João Victor, Prodonoff, Juliana Silveira, Carregari, Victor Corasolla, de Biagi Junior, Carlos Alberto Oliveira, Crunfli, Fernanda, Jimenez Restrepo, Jeffersson Leandro, Vendramini, Pedro Henrique, Reis-de-Oliveira, Guilherme, Bispo dos Santos, Karina, Toledo-Teixeira, Daniel A., Parise, Pierina Lorencini, Martini, Matheus Cavalheiro, Marques, Rafael Elias, Carmo, Helison R., Borin, Alexandre, Coimbra, Laís Durço, Boldrini, Vinícius O., Brunetti, Natalia S., Vieira, Andre S., Mansour, Eli, Ulaf, Raisa G., Bernardes, Ana F., Nunes, Thyago A., Ribeiro, Luciana C., Palma, Andre C., Agrela, Marcus V., Moretti, Maria Luiza, Sposito, Andrei C., Pereira, Fabrício Bíscaro, Velloso, Licio Augusto, Vinolo, Marco Aurélio Ramirez, Damasio, André, Proença-Módena, José Luiz, Carvalho, Robson Francisco, Mori, Marcelo A., Martins-de-Souza, Daniel, Nakaya, Helder I., Farias, Alessandro S., Moraes-Vieira, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367032/
https://www.ncbi.nlm.nih.gov/pubmed/32697943
http://dx.doi.org/10.1016/j.cmet.2020.07.007