A Long Non-coding RNA, LOC157273, Is an Effector Transcript at the Chromosome 8p23.1-PPP1R3B Metabolic Traits and Type 2 Diabetes Risk Locus

AIMS: Causal transcripts at genomic loci associated with type 2 diabetes (T2D) are mostly unknown. The chr8p23.1 variant rs4841132, associated with an insulin-resistant diabetes risk phenotype, lies in the second exon of a long non-coding RNA (lncRNA) gene, LOC157273, located 175 kilobases from PPP1...

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Detalles Bibliográficos
Autores principales: Manning, Alisa K., Goustin, Anton Scott, Kleinbrink, Erica L., Thepsuwan, Pattaraporn, Cai, Juan, Ju, Donghong, Leong, Aaron, Udler, Miriam S., Brown, James Bentley, Goodarzi, Mark O., Rotter, Jerome I., Sladek, Robert, Meigs, James B., Lipovich, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367044/
https://www.ncbi.nlm.nih.gov/pubmed/32754192
http://dx.doi.org/10.3389/fgene.2020.00615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367044/
https://www.ncbi.nlm.nih.gov/pubmed/32754192
http://dx.doi.org/10.3389/fgene.2020.00615

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