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Cytosolic NUAK1 Enhances ATP Production by Maintaining Proper Glycolysis and Mitochondrial Function in Cancer Cells

NUAK1 is an AMPK-related kinase located in the cytosol and the nucleus, whose expression associates with tumor malignancy and poor patient prognosis in several cancers. Accordingly, NUAK1 was associated with metastasis because it promotes cell migration and invasion in different cancer cells. Beside...

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Detalles Bibliográficos
Autores principales: Escalona, Emilia, Muñoz, Marcelo, Pincheira, Roxana, Elorza, Álvaro A., Castro, Ariel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367139/
https://www.ncbi.nlm.nih.gov/pubmed/32754444
http://dx.doi.org/10.3389/fonc.2020.01123