NFI Transcription Factors Provide Chromatin Access to Maintain Stem Cell Identity While Preventing Unintended Lineage Fate Choices

Tissue homeostasis and regeneration rely upon resident stem cells (SCs), whose behavior is regulated through niche-dependent crosstalk. The mechanisms underlying SC identity are still unfolding. Here, using spatiotemporal gene ablation in murine hair follicles (HFs), we uncover a critical role for t...

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Detalles Bibliográficos
Autores principales: Adam, Rene C., Yang, Hanseul, Ge, Yejing, Infarinato, Nicole R., Gur-Cohen, Shiri, Miao, Yuxuan, Wang, Ping, Zhao, Yilin, Lu, Catherine P., Kim, Jeong E., Ko, Joo Y., Paik, Seung S., Gronostajski, Richard M., Kim, Jaehwan, Krueger, James G., Zheng, Deyou, Fuchs, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367149/
https://www.ncbi.nlm.nih.gov/pubmed/32393888
http://dx.doi.org/10.1038/s41556-020-0513-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367149/
https://www.ncbi.nlm.nih.gov/pubmed/32393888
http://dx.doi.org/10.1038/s41556-020-0513-0

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