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NFI Transcription Factors Provide Chromatin Access to Maintain Stem Cell Identity While Preventing Unintended Lineage Fate Choices
Tissue homeostasis and regeneration rely upon resident stem cells (SCs), whose behavior is regulated through niche-dependent crosstalk. The mechanisms underlying SC identity are still unfolding. Here, using spatiotemporal gene ablation in murine hair follicles (HFs), we uncover a critical role for t...
Autores principales: | Adam, Rene C., Yang, Hanseul, Ge, Yejing, Infarinato, Nicole R., Gur-Cohen, Shiri, Miao, Yuxuan, Wang, Ping, Zhao, Yilin, Lu, Catherine P., Kim, Jeong E., Ko, Joo Y., Paik, Seung S., Gronostajski, Richard M., Kim, Jaehwan, Krueger, James G., Zheng, Deyou, Fuchs, Elaine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367149/ https://www.ncbi.nlm.nih.gov/pubmed/32393888 http://dx.doi.org/10.1038/s41556-020-0513-0 |
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