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A Rare Complex BRAF Mutation Involving Codon V600 and K601 in Primary Cutaneous Melanoma: Case Report

BRAF is one of the most common mutated kinases detected in human cancer, particularly in cases of primary cutaneous melanomas (PCM). Mutations of the BRAF proto-oncogene, at the p.V600 codon, has been detected in more than 50% of primary and metastatic melanoma cells in clinical samples. In addition...

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Detalles Bibliográficos
Autores principales: Consoli, Francesca, Barbieri, Gianluca, Picciolini, Matteo, Medicina, Daniela, Bugatti, Mattia, Tovazzi, Valeria, Liserre, Barbara, Zambelli, Claudia, Zorzi, Fausto, Berruti, Alfredo, Giurisato, Emanuele, Vermi, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367153/
https://www.ncbi.nlm.nih.gov/pubmed/32754440
http://dx.doi.org/10.3389/fonc.2020.01056