Full length RTEL1 is required for the elongation of the single-stranded telomeric overhang by telomerase

Telomeres cap the ends of eukaryotic chromosomes and distinguish them from broken DNA ends to suppress DNA damage response, cell cycle arrest and genomic instability. Telomeres are elongated by telomerase to compensate for incomplete replication and nuclease degradation and to extend the proliferati...

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Detalles Bibliográficos
Autores principales: Awad, Aya, Glousker, Galina, Lamm, Noa, Tawil, Shadi, Hourvitz, Noa, Smoom, Riham, Revy, Patrick, Tzfati, Yehuda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367169/
https://www.ncbi.nlm.nih.gov/pubmed/32542379
http://dx.doi.org/10.1093/nar/gkaa503

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367169/
https://www.ncbi.nlm.nih.gov/pubmed/32542379
http://dx.doi.org/10.1093/nar/gkaa503

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