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Orthogonal tuning of gene expression noise using CRISPR–Cas

The control of gene expression noise is important for improving drug treatment and the performance of synthetic biological systems. Previous work has tuned gene expression noise by changing the rate of transcription initiation, mRNA degradation, and mRNA translation. However, these methods are invas...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Shim, Jiyoung, Gong, Ting, Tan, Cheemeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367181/
https://www.ncbi.nlm.nih.gov/pubmed/32479612
http://dx.doi.org/10.1093/nar/gkaa451