DNA binds to a specific site of the adhesive blood-protein von Willebrand factor guided by electrostatic interactions

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Neutrophils release their intracellular content, DNA included, into the bloodstream to form neutrophil extracellular traps (NETs) that confine and kill circulating pathogens. The mechanosensitive adhesive blood protein, von Willebrand Factor (vWF), interacts with the extracellular DNA of NETs to pot...

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Detalles Bibliográficos
Autores principales: Sandoval-Pérez, Angélica, Berger, Ricarda M L, Garaizar, Adiran, Farr, Stephen E, Brehm, Maria A, König, Gesa, Schneider, Stefan W, Collepardo-Guevara, Rosana, Huck, Volker, Rädler, Joachim O, Aponte-Santamaría, Camilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367192/
https://www.ncbi.nlm.nih.gov/pubmed/32496552
http://dx.doi.org/10.1093/nar/gkaa466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367192/
https://www.ncbi.nlm.nih.gov/pubmed/32496552
http://dx.doi.org/10.1093/nar/gkaa466

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