Nucleosome binding by the pioneer transcription factor OCT4

Transcription factor binding to genomic DNA is generally prevented by nucleosome formation, in which the DNA is tightly wrapped around the histone octamer. In contrast, pioneer transcription factors efficiently bind their target DNA sequences within the nucleosome. OCT4 has been identified as a pion...

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Detalles Bibliográficos
Autores principales: Echigoya, Kenta, Koyama, Masako, Negishi, Lumi, Takizawa, Yoshimasa, Mizukami, Yuka, Shimabayashi, Hideki, Kuroda, Akari, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367260/
https://www.ncbi.nlm.nih.gov/pubmed/32678275
http://dx.doi.org/10.1038/s41598-020-68850-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367260/
https://www.ncbi.nlm.nih.gov/pubmed/32678275
http://dx.doi.org/10.1038/s41598-020-68850-1

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