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Gene–methylation interactions: discovering region-wise DNA methylation levels that modify SNP-associated disease risk

BACKGROUND: Current technology allows rapid assessment of DNA sequences and methylation levels at a single-site resolution for hundreds of thousands of sites in the human genome, in thousands of individuals simultaneously. This has led to an increase in epigenome-wide association studies (EWAS) of c...

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Detalles Bibliográficos
Autores principales: Romanowska, Julia, Haaland, Øystein A., Jugessur, Astanand, Gjerdevik, Miriam, Xu, Zongli, Taylor, Jack, Wilcox, Allen J., Jonassen, Inge, Lie, Rolv T., Gjessing, Håkon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367265/
https://www.ncbi.nlm.nih.gov/pubmed/32678018
http://dx.doi.org/10.1186/s13148-020-00881-x