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Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation

Triple-knockout (TKO) pigs may be ideal sources of organs for clinical xenotransplantation because many humans have no preformed antibody to TKO pig cells. Intravenous immunoglobulin (IVIg) is widely used for severe infection or the treatment/prevention of antibody-mediated rejection in allotranspla...

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Detalles Bibliográficos
Autores principales: Yamamoto, Takayuki, Cui, Yehua, Patel, Diyan, Jagdale, Abhijit, Iwase, Hayato, Ayares, David, Cooper, David K. C., Hara, Hidetaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367287/
https://www.ncbi.nlm.nih.gov/pubmed/32678137
http://dx.doi.org/10.1038/s41598-020-68505-1