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Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation
Triple-knockout (TKO) pigs may be ideal sources of organs for clinical xenotransplantation because many humans have no preformed antibody to TKO pig cells. Intravenous immunoglobulin (IVIg) is widely used for severe infection or the treatment/prevention of antibody-mediated rejection in allotranspla...
Autores principales: | Yamamoto, Takayuki, Cui, Yehua, Patel, Diyan, Jagdale, Abhijit, Iwase, Hayato, Ayares, David, Cooper, David K. C., Hara, Hidetaka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367287/ https://www.ncbi.nlm.nih.gov/pubmed/32678137 http://dx.doi.org/10.1038/s41598-020-68505-1 |
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