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Characterization of extended-spectrum-β-lactamase producing Klebsiellapneumoniae phage KP1801 and evaluation of therapeutic efficacy in vitro and in vivo

Extended spectrum β lactamase-producing Klebsiella pneumoniae (ESBL-KP) is being reported with high morbidity and mortality rates and is considered as the highest priority for new antimicrobial strategies. To develop an alternative antimicrobial agent, phage KP1801 with broad lytic activity was isol...

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Detalles Bibliográficos
Autores principales: Wintachai, Phitchayapak, Naknaen, Ampapan, Thammaphet, Jirapath, Pomwised, Rattanaruji, Phaonakrop, Narumon, Roytrakul, Sittiruk, Smith, Duncan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367294/
https://www.ncbi.nlm.nih.gov/pubmed/32678251
http://dx.doi.org/10.1038/s41598-020-68702-y