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“Oil-soluble” reversed lipid nanoparticles for oral insulin delivery
BACKGROUND: In this study, we aimed to design a novel oral insulin delivery system, named “oil-soluble” reversed lipid nanoparticles (ORLN), in which a hydrophilic insulin molecule is encapsulated by a phospholipid (PC) shell and dissolved in oil to prevent the enzymatic degradation of insulin. ORLN...
Autores principales: | Wang, Tao, Shen, Liao, Zhang, Yadan, Li, Haiyan, Wang, Yongan, Quan, Dongqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367322/ https://www.ncbi.nlm.nih.gov/pubmed/32680576 http://dx.doi.org/10.1186/s12951-020-00657-8 |
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