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Photosensitive and pH-dependent activity of pyrazine-functionalized carbazole derivative as promising antifungal and imaging agent

Carbazole skeleton plays a significant role as a structural scaffold of many pharmacologically active compounds. Pyrazine-functionalized carbazole derivative was constructed by coupling 2-amino-5-bromo-3-methylaminepyrazine (ABMAP) into 3 and 6 positions of the carbazole ring. Multi-experimental met...

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Detalles Bibliográficos
Autores principales: Chylewska, Agnieszka, Dąbrowska, Aleksandra M., Ramotowska, Sandra, Maciejewska, Natalia, Olszewski, Mateusz, Bagiński, Maciej, Makowski, Mariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367338/
https://www.ncbi.nlm.nih.gov/pubmed/32678219
http://dx.doi.org/10.1038/s41598-020-68758-w