Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

BACKGROUND: Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy. The aim of the study was to assess neurotoxicity of bupivacaine and liposome...

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Detalles Bibliográficos
Autores principales: Markova, Liljana, Umek, Nejc, Horvat, Simon, Hadžić, Admir, Kuroda, Max, Pintarič, Tatjana Stopar, Mrak, Vesna, Cvetko, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367396/
https://www.ncbi.nlm.nih.gov/pubmed/32680505
http://dx.doi.org/10.1186/s12917-020-02459-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367396/
https://www.ncbi.nlm.nih.gov/pubmed/32680505
http://dx.doi.org/10.1186/s12917-020-02459-4

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