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Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice
BACKGROUND: Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy. The aim of the study was to assess neurotoxicity of bupivacaine and liposome...
Autores principales: | Markova, Liljana, Umek, Nejc, Horvat, Simon, Hadžić, Admir, Kuroda, Max, Pintarič, Tatjana Stopar, Mrak, Vesna, Cvetko, Erika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367396/ https://www.ncbi.nlm.nih.gov/pubmed/32680505 http://dx.doi.org/10.1186/s12917-020-02459-4 |
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