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An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence

Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms. Therefore, it is important to identify new drug targets for drug discovery and novel therapeutics. Arv1 (are1 are2 required for viability 1)...

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Detalles Bibliográficos
Autores principales: Villasmil, Michelle L., Barbosa, Antonio Daniel, Cunningham, Jessie Lee, Siniossoglou, Symeon, Nickels, Joseph T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367482/
https://www.ncbi.nlm.nih.gov/pubmed/32678853
http://dx.doi.org/10.1371/journal.pone.0235746