Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain

To date, microglia subsets in the healthy CNS have not been identified. Utilizing autofluorescence (AF) as a discriminating parameter, we identified two novel microglia subsets in both mice and non-human primates, termed autofluorescence-positive (AF(+)) and negative (AF(−)). While their proportion...

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Detalles Bibliográficos
Autores principales: Burns, Jeremy Carlos, Cotleur, Bunny, Walther, Dirk M, Bajrami, Bekim, Rubino, Stephen J, Wei, Ru, Franchimont, Nathalie, Cotman, Susan L, Ransohoff, Richard M, Mingueneau, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367682/
https://www.ncbi.nlm.nih.gov/pubmed/32579115
http://dx.doi.org/10.7554/eLife.57495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367682/
https://www.ncbi.nlm.nih.gov/pubmed/32579115
http://dx.doi.org/10.7554/eLife.57495

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