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Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain
To date, microglia subsets in the healthy CNS have not been identified. Utilizing autofluorescence (AF) as a discriminating parameter, we identified two novel microglia subsets in both mice and non-human primates, termed autofluorescence-positive (AF(+)) and negative (AF(−)). While their proportion...
Autores principales: | Burns, Jeremy Carlos, Cotleur, Bunny, Walther, Dirk M, Bajrami, Bekim, Rubino, Stephen J, Wei, Ru, Franchimont, Nathalie, Cotman, Susan L, Ransohoff, Richard M, Mingueneau, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367682/ https://www.ncbi.nlm.nih.gov/pubmed/32579115 http://dx.doi.org/10.7554/eLife.57495 |
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