Itraconazole inhibits the Hedgehog signaling pathway thereby inducing autophagy-mediated apoptosis of colon cancer cells

Itraconazole is as an antifungal medication used to treat systemic fungal infections. Recently, it has been reported to be effective in suppressing tumor growth by inhibiting the Hedgehog signaling pathway and angiogenesis. In the present study, we investigated whether itraconazole induces autophagy...

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Detalles Bibliográficos
Autores principales: Deng, Huiming, Huang, Ling, Liao, Zhongkai, Liu, Mi, Li, Qiang, Xu, Ronghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367825/
https://www.ncbi.nlm.nih.gov/pubmed/32681018
http://dx.doi.org/10.1038/s41419-020-02742-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367825/
https://www.ncbi.nlm.nih.gov/pubmed/32681018
http://dx.doi.org/10.1038/s41419-020-02742-0

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