Cargando…
ECRG2, a novel transcriptional target of p53, modulates cancer cell sensitivity to DNA damage
Esophageal Cancer-Related Gene 2 (ECRG2) is a recently identified tumor suppressor, its regulation and involvement in DNA damage response are unknown. Here, we show that DNA damage-induced ECRG2 upregulation coincided with p53 activation and occurred in a p53-dependent manner. We identified two p53-...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367829/ https://www.ncbi.nlm.nih.gov/pubmed/32681017 http://dx.doi.org/10.1038/s41419-020-2728-1 |